Allergy Relief Information
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The following allergy relief information has been compiled from a
variety of resources in order to give you an overview of allergies,
allergy symptoms, allergy treatment medicines, etc.
An allergy is defined as an abnormally high
sensitivity to certain substances, such as pollens, foods, or
microorganisms. Common indications of allergy may include sneezing,
itching, and skin rashes.
Allergies represent one of the most common medical
disorders, an estimated one in five individuals suffer from some form of
allergies. Reports indicate that allergies are the most common reason
for absence from work in adults.

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Allergies can be distinguished into three types based on there reaction
time:
- Anaphylaxis - represents an allergic
reaction that occurs in minutes. Local symptoms can include
urticaria, mucosal swelling and secretions, circulatory shock, spasm
of the bronchial muscles (asthma), etc. Anaphylaxis is an allergic
reaction to antigens (e.g. foreign proteins, drugs, etc.) with which
the body as been previously exposed.
- Type E antibodies (IgE) - induced at the
initial contact bind to cells with IgE receptors, chiefly mast cells
and basophilic granulocytes. If an antigen-antibody reacts occurs at
the second contact, the granules of these cells release histamine
and other substances that contribute to the immune response. In
extreme case the release of histamine can result in anaphylactic
shock or a sudden, severe allergic reaction characterized by a sharp
drop in blood pressure, urticaria, and breathing difficulties that
is caused by exposure to a foreign substance, such as a drug or bee
venom, after a preliminary or sensitizing exposure. The reaction may
be fatal if emergency treatment, including epinephrine injections,
is not given immediately.
- Immune complex reaction -
represent an allergic reaction that occurs in hours or days. A
common type of immune complex reaction would be a skin reaction that
proceeds to necrosis, serum disease with fever, urticaria, swelling
of the lymph nodes and joints, proteinuria, etc.
- Delayed type reaction
- were the reaction time can be days to weeks. Local symptoms in the
delayed type reaction including flushing, fever, nausea, etc. This
type of reaction is characterized by the reaction to poison ivy.

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Allergy Relief Medicine
The primary goal of allergy treatment is to reduce
allergy symptoms caused by the inflammation of affected tissues. The
best treatment of allergies is to avoid the things that you are
allergens that are responsible for your symptoms. However, in many cases
it is nearly impossible to avoid these allergens.
Today, the primary treatment of allergies is
the use of medications:
Short-acting antihistamines
Short-acting antihistamines are generally over the
counter medications that can relieve mild to moderate symptoms. However,
these antihistamines usually cause drowsiness, Benedryl
(diphenhydramine) is an example of a short-acting antihistamine.
Long Acting Antihistamines
Long-acting antihistamines are usually
prescription medications that can relieve the symptoms of more severe
allergy symptoms. These antihistamines provide excellent relief from
common allergy symptoms for most individuals. Examples of long-acting
antihistamines include Allegra (fexofenadine), Zyrtec, (cetirizine),
Claritin (loratadine).
Distinct
from the current over-the-counter and many prescription antihistamines,
Allegra D, provides relief without causing drowsiness. In
fact, regulations require all antihistamines that cause drowsiness to
caution users concerning the operation of a motor vehicle or heavy
machinery. Allegra D does not carry any such label.
A common question is what is the difference
between Allegra and
Allegra D? The difference is Allegra-D combines antihistamine with
the nasal decongestant pseudoephedrine. The psuedoephedrine causes a
narrowing of the blood vessels in the nose this leads to a clearing of
the nasal congestion. This is why so many doctors prefer Allegra D over
Allegra.
Allegra D is an antihistamine that works by
blocking the action on histamine, when antibodies latch onto mast cells,
the mast cells release histamine, a chemical that causes blood vessels
in the nose to dilate and leak fluid into surrounding tissue. This
results in swelling, itching and nasal discharge. By blocking the
release of histamine these symptoms are decreased.

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Decongestants
Decongestants may also be useful in reducing
allergy symptoms. Decongestants are offered in an oral pill and a nasal
spray. However, nasal spray decongestants should not be prescribed for
more than several days, secondary to the potential for a "rebound"
effect which will make the congestion worse. Once "rebound" effect has
occurred the nose remains stuffy or gets worse with every dose. The only
way to stop the cycle is to stop using the medication. The stuffiness
should then go away within about a week. Individuals that who show signs
of severe rebound congestion should also contact his or her physician.
Some decongestants cause drowsiness.
Individuals who take decongestants medications should not drive, use
machines or do anything else that might be dangerous until they have
found out how the medication might effect their judgment.
Mast Cell Stabilizers
Cromolyn sodium prevents the release of mast cell
granules, thereby preventing the release of histamine and other
chemicals contained in them. Cromolyn acts as a preventive treatment if
it is started several weeks before the onset of the allergy season.
Cromolyn can also be used for year round allergy prevention. Cromolyn
sodium is available as a nasal spray (Nasalcrom) for allergic rhinitis,
aerosol form for asthma , eye drops for itchy, bloodshot eyes.
Corticosteroids
Corticosteroid are often used individuals with
symptoms not relieved by antihistamines and decongestants, nasal
corticosteroid sprays can offer significant relief. Inhaled steroids are
synthetic steroids that can be taken in through the nose or mouth. These
steroid medications reduce the inflammation in either your lungs, which
associated with asthma and/or your nose, associated with nasal
allergies. Examples of prescription corticosteroid sprays include:
Nasacort AQ (triamcinolone), Flonase (fluticasone), Nasonex
(mometasone).
Immunotherapy (injections)
Immunotherapy is a process in which an allergic
patient can become desensitized to those pollens and inhalants that
trigger allergic conjunctivitis, allergic rhinitis (nasal congestion),
asthma, insect reactions, etc. Small doses of the actual allergic
substance are injected into the patient on a weekly basis (each week the
dose is gradually increased). Gradually a protective antibody, also
known as Immunoglobulin G, is formed to block the allergic reaction.
When someone has allergy, they have high levels of the allergic
antibody, Immunoglobulin E (IgE), in their blood. This IgE is activated
by the allergen e.g. ragweed, dust mites, cat, etc), and it attaches
itself to “mast” cells that release histamine. The histamine causes a
release of a fluid that causes swelling and congestion. Histamine can
also cause a tightening of the airways to create asthma.
The change induced by immunotherapy represents a
slow process. Most patients begin to notice an improvement within six
months of treatment. Clinical studies show that immunotherapy is
beneficial in some 95% of patients who were correctly diagnosed to have
allergies.
Long-acting antihistamines represent the allergy
treatment of choice for most physicians. These medications will
relieve the symptoms of most allergy symptoms. Without question, Zyrtec
is the allergy treatment drug of choice.
Allergy Relief Medicine Conclusions
Allegra
D provides effective relief from the symptoms of seasonal allergies
including itchy, watery eyes; itchy palate; sneezing and runny nose.
Allegra is also effective in relieving the symptoms of itching
associated with chronic hives. So whether you suffer from allergies
secondary to dogs, cats, pets, pollen, ragweed, dander, mildew, dust,
mold, feathers, etc. Allegra D will provide relief.
In addition, Allegra D represents an allergy
relief medicine that relieves all the allergy symptoms without making
you drowsy.

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Prevention of allergies
Clinical studies have shown a genetic disposition
to suffering from allergies. Although allergies cannot be prevented,
recent information suggests that there are steps a family with a history
of allergic disease can take to delay or reduce the occurrence of
allergies their children
Entry of Allergens
Allergens enter the body through four main routes
including the airways, circulatory system, skin and the gastrointestinal
tract. Individuals with allergies are not equally sensitive to all
allergens. Allergies may wax and wane over time e.g. a childhood ragweed
allergy may progress to year round dust and pollen allergy. While an
individual may lose sensitivity to an allergen e.g. a child with atopic
dermatitis that gradually disappears as the child ages.
Cause of Allergies
The exact reason why specific allergies develop is
unknown, however, the cause of allergy symptoms is a direct response of
the immune system. Generally, the immune system seeks, recognizes and
fights viruses, bacteria, and other intruders.
The body's main defense against bacteria,
viruses, etc. are specialized molecules called antibodies. These
antibodies include lymphocytes or the white blood cells produced in the
bone morrow. The lymphocytes interact with antigens and release specific
antibodies that attack the antigens.
Whenever lymphocytes are activated a few of them
become what is known as "memory" cells. These "memory" cells are
programmed to remember antigens and destroy them when they reenter the
body. This represents the long-term memory which is referred to as
acquired immunity and is the reason most individuals do not fall prey to
the same virus or bacteria over and over.
Since individuals encounter such a wide variety of foreign
substance each day via their beverages, food, medications, etc. the
immune system is not designed to attack every foreign entrant. Instead,
the immune system selectively seeks out only those germs or invading
antigens that are perceived as potentially dangerous to the body.
Therefore, when you inherit the genetic tendency to develop allergies,
the immune system selectively misreads foreign substances, as being
dangerous. Antibodies then react to what should be harmless food,
pollen, chemicals, or other allergens causing an immune response. This
immune response is what is responsible for the common allergy symptoms
that effect so many individuals.
The
mediating chemicals e.g. histamine from the immune response are
responsible for the aggravating
symptoms of allergic reactions. Histamine released in the nose,
sinuses and eyes are are responsible for sneezing, runny nose,
congestion and irritated eyes. Histamine in the skin provokes the rashes
and hives associated with an allergic response, while the histamine in
the digestive system promotes stomach cramps and diarrhea.
The duration and intensity of the allergic
response is believed to be related to the quantity of histamine (and
other immune chemicals), an individuals genetic makeup (there is a link
between inheritance and allergies. If neither parent has allergies then
less than 20% of their children will have allergies. If one parent has
allergies there is a 50/50 chance that any given child will have
allergies. If both parents have allergies there is about a 75% chance
that each child will have allergies), and the total level of IgE to a
particular allergen.

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The primary allergens that initiate the immune
response can be divided into three categories including contact
dermatitis allergens, food allergens and airborne allergens:
Common allergens that cause contact dermatitis
include the following:
- Latex
- Posen ivy
- Oak
- Sumac
- nickel or nickel alloys
Common food allergens include the following:
- Nuts, (primarily walnuts, peanuts, Brazil
nuts)
- Fish
- Mollusks
- Shellfish
- Eggs
- Wheat
- Milk
- Food preservatives and additives
The most common airborne allergens are the
following:
- House mites
- Plant pollens
- Cigarette smoke
- Animal fur and dander
- Cleaners and solvents
- Household dust
- Mold spores
In addition, insects and other arthropods whose
bites/stings can often cause allergic reactions:
- mosquitoes
- fleas
- bees, wasps, and hornets
- scabies
Allergy Symptoms
Allergy symptoms can vary widely, from mild
discomfort to chronic sinusitis, allergic conjunctivitis and asthma.
Some individuals suffer seasonal allergic reactions, while others suffer
from hay fever symptoms year-round.
The most common allergy symptoms include the following:
- Sneezing
- Runny nose
- Post nasal drip
- Coughing
- Watery eyes
- Sinus headaches
- Impaired sense of smell
- Dark circles under the eyes
- Itching sensation around the eyes, throat,
mouth, nose and ears.
- Gastrointestinal symptoms (swelling and
tingling in the lips, tongue, palate or throat, cramping, nausea,
gas, diarrhea)
- Contact dermatitis (reddened, itchy, weepy,
blistered skin).
In addition, asthma attacks are often triggered by
allergens that are inhaled into the airways. Allergens may cause
inflammation and narrowing of the bronchial tubes. The result is often a
feeling of tightness in the chest, shortness of breath, wheezing, and
coughing.
Diagnosis of Allergies
Medical history
Allergies are often diagnosed by a thorough and
complete medical history which should include at least the following
questions:
- Family history (who has had a history of
allergies in your immediate family).
- Symptoms and their circumstances (where and
when do you have).
- Habits at home
- Professional and leisure activities
- Pets owned by the family
- Environment (house, garden, surrounding).
- General state of health (medical history,
prescription medications, over the counter medications).
Skin tests
Skin tests involve introducing small quantities of
very pure allergen of known concentrations into the skin (usually on
your inside forearm or on your back) and observing the reaction. There
are three types of skin test that are commonly used:
- Prick Test - this test involves placing
a drop of allergen on the skin, pricking the skin with a needle
point through the drop so that the allergen can get inside.
- Scratch Test
- the physician makes a tiny cut or superficial incision into the
skin, then deposits a tiny drop of allergen inside.
- Intradermal Test
- the allergen is injected under the skin by a syringe with a very
fine needle.
In all three methods, only very dilute
preparations of allergens are used to so that the reaction will be mild.
The physician can measure and interpret the reaction after approximately
20 - 30 minutes from the initial testing. If the reaction is positive,
he/she will see a wheal (tiny swelling), erythema (redness), individuals
may also experience pruritus (itching).
Blood test
Blood tests are commonly used to asses specific
IgE (immunoglubulin E). This involves detecting the presence of these
antibodies directed against specific allergens and measuring their
quantity.
Blood is drawn from the patient and then test is
conducted by mixing the serum with particles coated with purified
allergen. If the correct allergen is presented, the IgE in the serum
will "stick" to the particle, forming an antigen-antibody complex. The
reaction is then analyzed to determine the severity of the allergen.
Some 200 different types of allergens can be used in these studies.
The advantage of the blood test is the individual
does not have to be exposed to the allergen.
Challenge Test
The principle of the challenge test is to
reproduce the symptoms of the allergic reaction by bringing the
individual into contact with the suspected allergen. If a reaction does
occur, it can be concluded that allergen is responsible for the allergy
symptoms.
However, challenge tests are conducted only there
are conflicting results with the medical history, skin tests, blood test
and other diagnostic procedures Challenge tests should be conducted in
special centers, because they may involve the risk of anaphylactic shock
or asthma attacks.
Food Allergies
You Food allergies in children can cause
severe allergic reactions, ranging from rashes to complete anaphylactic
shock. The major strategy for preventing food allergies is to delay
exposure to potentially allergenic foods and beverages. Since newborn
infants may be more susceptible to food sensitization than older infants
mothers should make an effort to continue to breast feed their infant
for at least four to six months. Breast milk is much less likely to
produce an allergic reaction and can strengthen the child’s immune
system. Infants not being breast fed or supplemented with breast milk,
protein hydrolysate formulas such as Nutramigen or Alimentum should be
supplied rather than milk or soy based formulas. Protein hydrolysate
formulas are essential pre-digested protein that have been shown in
clinical studies to be less likely to trigger an immune response.
In addition, infants should not be given any
solid foods until they are at least six months old. Then once a child is
between the ages of six to twelve months vegetables, meat, rice and
fruit can be introduced to their diets. Each new food should be
introduced one at a time to monitor for any allergic reaction. After 12
months of age milk, wheat, citrus, corn and soy products can be added to
the diet. Finally after 24 months fish and eggs can be added to the
diet, peanuts should not be introduced until after 36 months.
This dietary regimen has been shown to
significantly reduce or delay food allergies and/or atopic dermatitis,
eczema, etc. in infants with a strong family history of allergies.
Environmental Allergies
Clinical studies have shown that there is an
increased risk of becoming allergic to certain substances in the
environment when an infant is exposed shortly after birth. This is
especially true for dust mites which are tiny microscopic creatures that
live in your house. Dust mites measure about 1/100th of an inch in
length, the waste of dust mites is the major cause of allergies and
asthma.
Dust mites live in warm and humid areas that tend
to be dusty. These areas include pillows, mattresses, carpets,
furniture, etc. Clinical studies have shown that taking aggressive
efforts to reduce dust mites can significantly reduce the occurrence of
allergies in young children.
Individuals can use plastic covers on pillows
and mattresses, wash all bedding in hot water at least once a week
(water used to wash your sheets and blankets should be 130°F). Indoor
relative humidity should be kept below fifty percent in attempt to limit
the dust mite population. Carpets, upholstered furniture or other
objects that collect dust should be removed from small childrens'
bedrooms.
Unfortunately, the development of allergies to
animals in children is associated with the presence of pets in the
children’s homes at birth. Animal allergies are triggered by proteins
found in the dander, saliva, urine, etc. of certain animals including
cats, dogs, rabbits and other rodents. For this reason, infants from
families with a strong history of allergy symptoms should not be exposed
to these indoor pets in an attempt to prevent allergies to animals.
Since allergies often trigger asthma, it is not
surprising that infants exposed to fewer dust mites during infancy are
less likely to develop allergic asthma. Hence, aggressive efforts to
control dust mites can significantly reduce the incidence of asthma and
upper respiratory allergies in young children. Exposure to pets during
infancy may also increase the risk of developing asthma, children should
not be exposed to household pets with fur during their first few years
of life.
Exposing children to secondhand smoke in the
home has also been shown to increase asthma and other chronic
respiratory illnesses during childhood. Some 99 percent of infants with
asthma have at least one parent who smokes. Therefore, it is very
important that infants are not exposed young children to second-hand
smoke.
Most parents are unaware that it is not just the
actual smoke that triggers the asthma, nicotine trapped in the clothes,
upholstery, cars, etc of smokers can also trigger and asthmatic
response.

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